Plasma-Amino-Acids Plasma-Amino-Acids
Plasma Amino Acids Plasma Amino Acids Plasma Amino Acids

Plasma Amino Acids

Amino acid (AA) nutritional testing analysis aids in the identification of dietary protein adequacy and amino acid balance, gastrointestinal dysfunctions, forms of protein intolerance, vitamin and mineral deficiencies, renal and hepatic dysfunction, psychiatric abnormalities, susceptibility to inflammatory response and oxidative stress, reduced detoxification capacity and many other inherent and acquired disorders in AA metabolism. Plasma is traditionally used to assess the status of essential AA while urine analysis provides more information regarding AA wasting and aberrant metabolism associated with co-factor insufficiencies. [ LEARN MORE]

Useful for:

    Turnaround Time

    3 to 5 days

    Analytes Tested

    Click any analyte name for additional clinical information, including reference ranges, specimen collection, stability and rejection criteria.

    Analyte
    CPT
    ABN Required
    1-Methylhistidine; plasma
    82139
    No
    3-Methylhistidine; plasma
    82139
    No
    A-Aminoadipate; plasma
    82139
    No
    A-Amino-n-butyrate; plasma
    82139
    No
    Alanine; plasma
    82139
    No
    Ammonia; plasma
    82139
    No
    Anserine; plasma
    82139
    No
    Arginine; plasma
    82139
    No
    Asparagine; plasma
    82139
    No
    Aspartic Acid; plasma
    82139
    No
    B-Alanine; plasma
    82139
    No
    B-Aminoisobutyrate; plasma
    82139
    No
    Carnosine; plasma
    82139
    No
    Citrulline; plasma
    82139
    No
    Cystathionine; plasma
    82139
    No
    Cystine; plasma
    82139
    No
    Ethanolamine; plasma
    82139
    No
    G-Aminobutyrate; plasma
    82139
    No
    Glutamic Acid; plasma
    82139
    No
    Glutamine; plasma
    82139
    No
    Glycine; plasma
    82139
    No
    Histidine; plasma
    82139
    No
    Homocystine; plasma
    82139
    No
    Hydroxyproline; plasma
    82139
    No
    Isoleucine; plasma
    82139
    No
    Leucine; plasma
    82139
    No
    Lysine; plasma
    82139
    No
    Met Sulfoxide; plasma
    82139
    No
    Methionine; plasma
    82139
    No
    Ornithine; plasma
    82139
    No
    Phenylalanine; plasma
    82139
    No
    Phosphoethanolamine; plasma
    82139
    No
    Phosphoserine; plasma
    82139
    No
    Proline; plasma
    82139
    No
    Sarcosine; plasma
    82139
    No
    Serine; plasma
    82139
    No
    Taurine; plasma
    82139
    No
    Threonine; plasma
    82139
    No
    Tryptophan; plasma
    82139
    No
    Tyrosine; plasma
    82139
    No
    Urea; plasma
    82139
    No
    Valine; plasma
    82139
    No

    List price applies when filing with insurance or Medicare, or when billing a patient directly. Prompt payment pricing applies when billing to a physician account or prepayment is received with the test.

    Doctor's Data offers profiles containing multiple analytes. *Multiple analytes may be billed under a single CPT code. Many analytes can be ordered individually. Pricing may vary. Click on a specific analyte for more information or read our detailed billing and payment policies.

    The CPT codes listed on our website are for informational purposes only. This information is our interpretation of CPT coding requirements and may not necessarily be correct. You are advised to consult the CPT Coding Manual published by the American Medical Association. Doctor's Data, Inc. takes no responsibility for billing errors due to your use of any CPT information from our website.

    Sign in at the top of any page to view pricing and order tests. Or click here to create an account. You may also contact us for assistance placing an order.

    Detailed Information

    Many individuals have "hidden" impairments in amino acid metabolism that are problematic and often go undiagnosed. These impairments may or may not be expressed as specific symptoms. They may silently increase susceptibility to a degenerative disease or they may be associated with, but not causative for, a disease. Because of the wealth of information provided, it is suggested that a complete amino acid analysis be performed whenever a thorough nutritional testing and a metabolic workup is called for.

    Amino acid analysis provides fundamental information about nutrient adequacy, including the quality and quantity of dietary protein, digestive disorders, and vitamin and mineral deficiencies—particularly folic acid, B12, B6 metabolism, zinc and magnesium. In addition, amino acid analysis provides important diagnostic information about hepatic and renal function, availability of precursors of neurotransmitters, detoxification capacity, susceptibility to occlusive arterial disease (homocystine), and many inherent disorders in amino acid metabolism.

    The patient's results are presented in a functional format that permits ease of interpretation. A comprehensive summary of "presumptive needs" (such as B6, B12/folate, Mg) and "implied conditions" (such as maldigestion/malabsorption, abnormal gastrointestinal flora, impaired detoxification, oxidative stress) are presented based upon each patient's results. Patient-specific amino acid supplement schedules and user-friendly commentary are provided to simplify nutritional intervention.

    Plasma vs. Urine Analysis
    Plasma is traditionally used to assess the status of essential AA while urine analysis provides more information regarding AA wasting and aberrant metabolism associated with co-factor insufficiencies.

    Plasma amino acid nutritional testing measures what is being transported at the time of sampling. The specimen should be collected after an overnight fast to reduce the influence of dietary protein. Abnormalities are deduced by comparison of measured levels with an established reference range.

    The 24-hour urine amino acid analysis has the highest probability of detecting abnormalities if renal function is normal. The 24-hour test indicates what is high and low over the course of a day, reflects blood and tissue amino acid pools, and is not affected by circadian rhythm. Healthy kidneys efficiently conserve essential amino acids. Therefore, urine levels of amino acids decrease first and tend to give an earlier indication of inadequacy than do plasma levels.

    A first morning void urine (FMV) amino acid analysis, with results normalized per gram creatinine, provides an alternative when a complete 24-hour collection is not a viable option. The FMV analysis is excellent for identification of marked abnormalities, particularly with respect to gastrointestinal health, inherited disorders in amino acid metabolism and renal function, and can be used for protein challenge testing.