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Urine Toxic & Essential Elements Urine Toxic & Essential Elements Urine Toxic & Essential Elements

Urine Toxic & Essential Elements

Urine Elements are traditionally used to evaluate exposure to potentially toxic elements and wasting of nutrient elements. Additionally, the comparison of urine element concentrations before and after administration of a chelator can be used to estimate net retention of potentially toxic elements. Subsequent urine element analyses, also following the administration of a chelator, are useful for monitoring the efficacy of metal detoxification therapy. Results are expressed per 24 hours or creatinine corrected to account for urine dilution effects [ LEARN MORE]

Useful for:

  • Toxic Element Exposure
  • Alopecia
  • Bone Density
  • Cardiovascular Disease
  • Depression
  • Dermatitis or Poor Wound Healing
  • Detoxifiction Therapy
  • Fatigue
  • Gastrointestinal Symptoms
  • Hypertension
  • Immune Function
  • Impaired Glucose Tolerance
  • Inflammation
  • Kidney Function
  • Nutritional Deficiencies
  • Parkinson's-like Symptoms

Turnaround Time

2 to 4 days

Analytes Tested

Click any analyte name for additional clinical information, including reference ranges, specimen collection, stability and rejection criteria.

Analyte
CPT
ABN Required
Aluminum; urine
82108
Yes
Antimony; urine
83018
Yes
Arsenic; urine
82175
Yes
Barium; urine
83018
Yes
Beryllium; urine
83018
Yes
Bismuth; urine
83018
Yes
Boron; urine
83018
Yes
Cadmium; urine
82300
Yes
Calcium; urine
83018
Yes
Cesium; urine
83018
Yes
Chromium; urine
82495
Yes
Cobalt; urine
83018
Yes
Copper; urine
82525
Yes
Gadolinium; urine
83018
Yes
Iron; urine
83540
Yes
Lead; urine
83655
Yes
Lithium; urine
80178
Yes
Magnesium; urine
83735
Yes
Manganese; urine
83785
Yes
Mercury; urine
83825
Yes
Molybdenum; urine
83018
Yes
Nickel; urine
83885
Yes
Palladium; urine
83018
Yes
Phosphorus; urine
84105
Yes
Platinum; urine
83018
Yes
Potassium; urine
84133
Yes
Selenium; urine
84255
Yes
Sodium; urine
84300
Yes
Strontium; urine
83018
Yes
Sulfur; urine
84999
Yes
Tellurium; urine
83018
Yes
Thallium; urine
83018
Yes
Thorium; urine
83018
Yes
Tin; urine
83018
Yes
Tungsten; urine
83018
Yes
Uranium; urine
83018
Yes
Vanadium; urine
83018
Yes
Zinc; urine
84630
Yes

List price applies when filing with insurance or Medicare, or when billing a patient directly. Prompt payment pricing applies when billing to a physician account or prepayment is received with the test. Doctor's Data offers profiles containing multiple analytes. *Multiple analytes may be billed under a single CPT code. Many analytes can be ordered individually. Pricing may vary. Click on a specific analyte for more information or read our detailed billing and payment policies. The CPT codes listed on our website are for informational purposes only. This information is our interpretation of CPT coding requirements and may not necessarily be correct. You are advised to consult the CPT Coding Manual published by the American Medical Association. Doctor's Data, Inc. takes no responsibility for billing errors due to your use of any CPT information from our website. Sign in at the top of any page to view pricing and order tests. Or click here to create an account. You may also contact us for assistance placing an order.

Doctor's Data offers profiles containing multiple analytes. *Multiple analytes may be billed under a single CPT code. Many analytes can be ordered individually. Pricing may vary. Click on a specific analyte for more information or read our detailed billing and payment policies.

The CPT codes listed on our website are for informational purposes only. This information is our interpretation of CPT coding requirements and may not necessarily be correct. You are advised to consult the CPT Coding Manual published by the American Medical Association. Doctor's Data, Inc. takes no responsibility for billing errors due to your use of any CPT information from our website.

Sign in at the top of any page to view pricing and order tests. Or click here to create an account. You may also contact us for assistance placing an order.

Detailed Information

Analysis of the levels of toxic metals in urine after the administration of a metal detoxification agent is an objective way to evaluate the accumulation of toxic metals. Acute metal poisoning is rare. More common, however, is a chronic, low-level exposure to toxic metals that can result in significant retention in the body that can be associated with a vast array of adverse health effects and chronic disease. One cannot draw valid conclusions about adverse health effects of metals without assessing net retention. For an individual, toxicity occurs when net retention exceeds physiological tolerance. Net retention is determined by the difference between the rates of assimilation and excretion of metals. To evaluate net retention, one compares the levels of metals in urine before and after the administration of a pharmaceutical metal detoxification agent such as EDTA, DMSA or DMPS. Different compounds have different affinities for specific metals, but all function by sequestering "hidden" metals from deep tissue stores and mobilizing the metals to the kidneys for excretion in the urine. It is important to perform both pre- and post-provocation urinalysis to permit distinction between ongoing exposures to metals (pre-) and net bodily retention. The pre-provocation urine collection can also be utilized to assess the rate of creatinine clearance if a serum specimen is also submitted. Many clinicians also request the analysis of essential elements in urine specimens to evaluate nutritional status and the efficacy of mineral supplementation during metal detoxification therapy. Metal detoxification agents can significantly increase the excretion of specific nutrient elements such as zinc, copper, manganese and molybdenum. Chromium metabolism authorities suggest that 24-hour chromium excretion likely provides the best assessment of chromium status. Early indication of renal dysfunction can be gleaned from urinary wasting of essential elements such as magnesium, calcium, potassium and sodium in an unprovoked specimen. Variability in urine volume can drastically affect the concentration of elements. To compensate for urine dilution variation, elements are expressed per unit creatinine for timed collections. For 24-hour collections, elements are reported as both units per 24 hours and units per creatinine.